3/1/2024 0 Comments Mucinex extra strength liquid![]() It has also been used as a component of OTC analgesics containing paracetamol.Īccording to one study, guaifenesin also works as a centrally acting muscle relaxant, preclinically and clinically. Given its expectorant nature, this agent is often used as a combination component of various prescription and non-prescription over-the-counter cough and cold medications and is a widely available over-the-counter generic medication used to temporarily relieve coughs caused by the common cold, bronchitis, asthma, and other breathing problems. Mucinex indirectly acts on the gastrointestinal vagal nerves, which trigger reflex secretion from submucosal glands and goblet cells - there, it affects mucus secretion from the goblet and Clara cells, resulting in reduced mucin production and secretion and mucus viscoelasticity, which increases the mucus layer’s hydration and loosening congestion in the chest and throat, making it easier for it to be coughed out. It was formally approved by the US FDA in 1952 and is one of the few drugs readily available and used as an expectorant. Acute renal failure after ingestion of guaifenesin and dextromethorphan.Mucinex is a brand name for guaifenesin and belongs to a class of medicines known as expectorants.
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